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In the antipathic (palliative) mode of treatment, however precisely the reverse of this takes place. The medicinal symptom which the physician opposes to the disease symptom (for example, the insensibility and stupefaction caused by opium in its primary action to acute pain) is certainly not alien, not allopathic of the latter; there is a manifest relation of the medicinal symptom to the disease symptom, but it is the reverse of what should be; it is here intended that the annihilation of the disease symptom shall be effected by an opposite medicinal symptom, which is impossible....The disease symptom (this single part of the disease) consequently becomes worse after the term of the action of the palliative has expired; worse in proportion to the magnitude of the dose of the palliative. § 69 Organon, Fifth Edition
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